Muscle weakness, aches and cramps are common in people with hypothyroidism. Although weakness can be generalized, people often experience it in muscles that are closest to the center of the body, such as the thigh or shoulder. This can cause problems climbing stairs or combing your hair. Hypothyroid myopathy is characterized by myalgia and weakness and affects nearly 80 percent of patients with hypothyroidism.
Patients with severe or untreated hypothyroidism may develop significant muscle disease, leading to severe functional limitations. This activity describes the presentation, evaluation, and treatment of hypothyroid myopathy and highlights the role of the interprofessional team in the treatment of patients with this condition. Muscle weakness can also be due to insulin resistance and, therefore, glucose has problems entering cells for use as energy. Remember that the thyroid keeps things moving, but it's also responsible for keeping many things in place in the body where they should be.
With hypothyroidism, fluid can build up in soft tissues and joints, which can cause stiffness and discomfort. Calcium may also have a harder time getting back to your muscles. What does that do? May cause prolonged muscle contractions. Hypothyroidism and hashimoto can cause joint and muscle pain.
Those of us with autoimmune hypothyroidism (Hashimoto's disease) have a higher risk of developing rheumatoid arthritis. When metabolism works slower than normal, due to underactive thyroid, less energy is produced, which causes the musculoskeletal system to feel pain and other associative symptoms. Fortunately, rhabdomyolysis is a rare complication of severe, untreated hypothyroid myopathy, but it can be life-threatening. In addition to the intense fatigue caused by hypothyroidism, numerous aches, stiffness and weakness have been reported in the joints (such as the knees and fingers, especially the thyroid, leg pain and weakness) and in the muscles (such as the calves, back and feet).
There is also a decrease in muscle carnitine in patients with thyroid dysfunction that causes myopathic symptoms. Changes in muscle cell membrane permeability can cause elevations in serum muscle enzymes in the absence of symptoms or structural abnormalities, and reduced elimination of these enzymes can also contribute to muscle injury. By better understanding the muscle symptoms of thyroid disease, you can control your discomfort or weakness. The increase in the number of internal nuclei, mitochondrial inclusions, glycogen accumulation, autophagic vacuoles and myofibrillar disorganization are other non-specific histopathological features that can be seen in muscle biopsy.
In addition to muscle symptoms, you may have a high level of creatinine kinase, which is measured by a blood test. Myopathy or muscle disease associated with hypothyroidism occurs due to underproduction of thyroxine (thyroid hormone). It is seen in both congenital and acquired hypothyroidism and is characterized by generalized myalgia and muscle weakness. Hypothyroid myopathy presents with nonspecific symptoms of myalgia, muscle cramps, fatigue and muscle weakness, which are particularly aggravated by exertion and exercise.
The exact cause of hypothyroidism-induced myopathy is unknown, but some experts believe that the thyroxine (T) deficiency seen in hypothyroidism causes muscle damage and impaired muscle function. Managing thyroid health, in addition to treating joint and muscle pain associated with hypothyroidism, can be extremely difficult at times. Rheumatologists are experts in joint and muscle problems and treat arthritis, certain autoimmune conditions, various musculoskeletal pain disorders, fibromyalgia and tendonitis. It has been observed that the degree of muscle weakness does not always correlate with the severity of thyroid hormone deficiency and this suggests that, in addition to the deterioration of muscle function, structural muscle injury could influence the pathogenesis of myopathy in some cases.